“Studies have shown that testosterone-replacement therapy may offer a wide range of benefits for men with hypogonadism, including improved libido, mood, cognition, muscle mass, bone density, and red blood cell production.”
“Using data from a prospective registry of 261 men (ages 32 to 84) with low testosterone (<12nmol/L), researchers examined 164 men for five years of testosterone therapy. After five years of follow up, the men had experienced statistically significant weight loss (mean weight decrease from 104.23 kg to 92.49 kg), decreases in body mass index (average 33.17 to 29.44) and waist circumference (average 108.61 to 99.03) as well as changes in total cholesterol, glucose and blood pressure levels.”
“Benefits of androgen replacement therapy include increased body hair and beard growth, energy, hematocrit, muscle mass, strength and stamina; increased ability to perform more physically demanding tasks; and an overall in- crease in the sense of well-being, confidence, and motivation.”
Large, robust randomized controlled trials have demonstrated efficacy of testosterone therapy compared with placebo for multiple parameters of sexual function. Other possible beneficial effects of testosterone therapy, such as reduced fracture risk and favorable effects on cognitive function and cardiovascular function, require further investigation.
“Conclusion: The protective effect of testosterone on myocardial ischaemia is maintained throughout treatment without decrement. Previously noted potentially beneficial effects of testosterone on body composition were confirmed and there were no adverse effects.